About
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Medicine (NDM) at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct.
Publications
-
Oligomerization-driven avidity correlates with SARS-CoV-2 cellular binding and inhibition.
Journal article
Asor R. et al, (2024), Proceedings of the National Academy of Sciences of the United States of America, 121
-
Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex
Preprint
Paesen GC. et al, (2024)
-
A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease.
Journal article
Avanzato VA. et al, (2024), Journal of virology
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Arctis pFIB-SEM
Krios G3i TEM with Falcon4i SelectrisX
Aquilos2+ FIB-SEM
ACDP3/DEFRA4 laboratories