Crystallographic fragment screen of Enterovirus D68 3C protease and iterative design of lead-like compounds using structure-guided expansions

Lithgo R., Tomlinson CWE., Fairhead M., Winokan M., Thompson W., Wild C., Aschenbrenner JC., Balcomb B., Marples P., Chandran A., Golding M., Koekemoer L., Williams E., Wang S., Ni X., MacLean E., Giroud C., Zarganes-Tzitzikas T., Godoy AS., Xavier M-A., Walsh M., Fearon D., von Delft F.

DOI

10.1101/2024.04.29.591650

Type

Preprint

Publication Date

2024

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