About
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Medicine (NDM) at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct.
Publications
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Covalently constrained 'Di-Gembodies' enable parallel structure solutions by cryo-EM.
Journal article
Yi G. et al, (2025), Nat Chem Biol
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The structure of the mammalian bornavirus polymerase complex
Journal article
Carrique L. et al, (2025), Nature Communications, 16
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Capsid Restructuring Activates Semi-Conservative dsRNA Transcription in Cystovirus ɸ6.
Journal article
Ilca SL. et al, (2025), bioRxiv
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Tomography
High resolution EM
CLEM
ACDP3/DEFRA4 laboratories