WELCOME
Overview
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Clinical Medicine at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct (see 'Contact us' tab for more details).
ACDP3/DEFRA4 containment laboratories
Krios G3i TEM with Falcon-4 SelectrisX
Aquillos2 SEM
PRIMO Micropatterning device
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Latest publications
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A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation.
Journal article
Bahar MW. et al, (2022), Commun Biol, 5
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Humoral responses against SARS-CoV-2 Omicron BA.2.11, BA.2.12.1 and BA.2.13 from vaccine and BA.1 serum.
Journal article
Huo J. et al, (2022), Cell discovery, 8
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Cryo‐EM
structures of perforin‐2 in isolation and assembled on a membrane suggest a mechanism for pore formation
Journal article
Yu X. et al, (2022), The EMBO Journal
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Production and Characterisation of Stabilised PV-3 Virus-like Particles Using Pichia pastoris.
Journal article
Sherry L. et al, (2022), Viruses, 14