WELCOME
Overview
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Clinical Medicine at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct (see 'Contact us' tab for more details).
ACDP3/DEFRA4 containment laboratories
Krios G3i TEM with Falcon4 SelectrisX
Aquillos2+ FIB-SEM
PRIMO Micropatterning device
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Latest publications
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ChAdOx1 COVID vaccines express RBD open prefusion SARS-CoV-2 spikes on the cell surface
Preprint
Zhang P. et al, (2023)
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Investigation of the milling characteristics of different focused-ion-beam sources assessed by three-dimensional electron diffraction from crystal lamellae.
Journal article
Parkhurst JM. et al, (2023), IUCrJ
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Protection against SARS-CoV-2 Omicron BA.4/5 variant following booster vaccination or breakthrough infection in the UK.
Journal article
Wei J. et al, (2023), Nature communications, 14
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Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography.
Journal article
Shah PNM. et al, (2023), Cell Host Microbe, 31, 604 - 615.e4