About
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Medicine (NDM) at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct.
Publications
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Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex.
Journal article
Paesen GC. et al, (2025), mBio
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Temporal correlations between RBD-ACE2 blocking and binding antibodies to SARS-CoV-2 variants in CoronaVac-vaccinated individuals and their persistence in COVID-19 patients.
Journal article
Poolchanuan P. et al, (2025), Sci Rep, 15
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Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories.
Journal article
Zwerwer LR. et al, (2025), Nature communications, 16
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Tomography
High resolution EM
CLEM
ACDP3/DEFRA4 laboratories