WELCOME
Overview
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Clinical Medicine at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct (see 'Contact us' tab for more details).
ACDP3/DEFRA4 containment laboratories
Krios G3i TEM with Falcon-4 SelectrisX
Aquillos2 SEM
PRIMO Micropatterning device
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Latest publications
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Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX.
Journal article
Shirasaki T. et al, (2022), PLoS pathogens, 18
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SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection.
Journal article
Wei J. et al, (2022), Nat Commun, 13
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Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum.
Journal article
Tuekprakhon A. et al, (2022), Cell
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Potent cross-reactive antibodies following Omicron breakthrough in vaccinees.
Journal article
Nutalai R. et al, (2022), Cell, 185, 2116 - 2131.e18