WELCOME
Overview
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Clinical Medicine at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request from academia and industry alike for competitive prices, and funding is available via Instruct (see 'Contact us' tab for more details).
Biosafety containment laboratories (ACDP3/DEFRA4)
Cell culture
Microscopy
Virus production and purification
Krios G3i Falcon-4 SelectrisX
Electron cryo-microscopy and tomography
Aquillos2
Scanning Electron-Microscopy Focussed-Ion Beam Milling
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Latest publications
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An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status
Journal article
Lumley SF. et al, (2022), Clinical Infectious Diseases, 74, 1208 - 1219
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Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies
Journal article
Ng WM. et al, (2022), mBio
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Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies
Ng W. et al, (2022)
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Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines
Journal article
Wei J. et al, (2022), Nature Medicine