About
The Oxford Particle Imaging Centre (OPIC) is part of the Division of Structural Biology (STRUBI) within the Nuffield Department of Medicine (NDM) at the University of Oxford.
OPIC offers a wealth of high resolution imaging resources for internal and external applicants.
Working in synergy with eBIC (Harwell, UK), we have the unique capability of preparing and collecting TEM data on BSL3 virus samples.
Access to our facility is available at request for academia and industry alike at competitive prices, and funding is available via Instruct.
Publications
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TomoCPT: a generalizable model for 3D particle detection and localization in cryo-electron tomograms
Journal article
Shah PNM. et al, (2025), Acta Crystallographica Section D Structural Biology, 81, 63 - 76
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DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts
Journal article
Kuś K. et al, (2025), Nature Communications, 16
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Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines.
Journal article
Sherry L. et al, (2025), Nature communications, 16
ACCESS
Access to this facility can be made directly through embookings@strubi.ox.ac.uk Please see Access Tab for pricing and further information.
Access for European researchers is also available through the Instruct-ERIC (pan-European Research Infrastructure in Structural Biology). Free at point of use through peer review.
Arctis pFIB-SEM
Krios G3i TEM with Falcon4i SelectrisX
Aquilos2+ FIB-SEM
ACDP3/DEFRA4 laboratories